Human chronic chagasic cardiopathy: participation of parasite antigens, subsets of lymphocytes, cytokines and microvascular abnormalities

Memórias do Instituto Oswaldo Cruz

Maria De Lourdes Higuchi¹ 

[1] ,Universidade de São PauloSão Paulo SP ,Brasil

关键词: Chagas disease;    myocarditis;    Trypanosoma cruzi;    immunodepression;   

DOI  :  10.1590/S0074-02761999000700044

来源: SciELO

【 摘 要 】

This article tries to demonstrate by new pathological findings (with the use of immunohistochemical technique and confocal laser microscopy) that chronic chagasic cardiomyopathy is a result of multiple factors involving myocarditis, immunodepression, severe fibrosis and microvessels dilatation and that all of these alterations are probably directly related with the presence of Trypanosoma cruzi parasites in the host associated with inadequate immunological response of the host.

【 授权许可】

CC BY   
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