Bloodmeal microfilariae density and the uptake and establishment of Wuchereria bancrofti infections in Culex quinquefasciatus and Aedes aegypti

Memórias do Instituto Oswaldo Cruz

Cleide Mr Albuquerque²  Vânia Ms Cavalcanti¹  Maria Alice V Melo²  Paulo Verçosa²  Lêda N Regis¹  Hilary Hurd¹ 

[1] ,Universidade Federal de PernambucoRecife PE ,Brasil

关键词: Culex quinquefasciatus;    Aedes aegypti;    Wuchereria bancrofti;    vectorial capacity;   

DOI  :  10.1590/S0074-02761999000500005

来源: SciELO

【 摘 要 】

The relationship between ingestion of microfilariae (mf), production of infective larvae (L3) and mf density in human blood has been suggested as an important determinant in the transmission dynamics of lymphatic filariasis. Here we assess the role of these factors in determining the competence of a natural vector Culex quinquefasciatus and a non vector Aedes aegypti to transmit Wuchereria bancrofti. Mosquitoes were infected via a membrane feeding procedure. Both mosquito species ingested more than the expected number of microfilariae (concentrating factor was 1.28 and 1.81 for Cx. quinquefasciatus and Ae. aegypti, respectively) but Cx. quinquefasciatus ingested around twice as many mf as Ae. aegypti because its larger blood meal size. Ae. aegypti showed a faster mf migration capacity compared to Cx. quinquefasciatus but did not allow parasite maturation under our experimental conditions. Similar proportions of melanized parasites were observed in Ae. aegypti (2.4%) and Cx. quinquefasciatus (2.1%). However, no relationship between rate of infection and melanization was observed. We conclude that in these conditions physiological factors governing parasite development in the thorax may be more important in limiting vectorial competence than the density of mf ingested.

【 授权许可】

CC BY   
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