Methodology in structural determination and synthesis of insect pheromone

Memórias do Instituto Oswaldo Cruz

Guo-qiang Lin¹  Wei-shan Zhou¹ 

[1] ,Chinese Academy of Sciences Shanghai Institute of Organic Chemistry Shanghai,China

关键词: insect pheromone;    isolation;    structure determination;    chiral synthesis;    chiral recognition;   

DOI  :  10.1590/S0074-02761991000600028

来源: SciELO

【 摘 要 】

By means of ethereal washing of insect pheromone glands of female moths, GC-MS detection along with microchemical reactions and electroantennogram (EAG) survey, six economically important insect species were targeted for pheromone identification. The discovery of a natural pheromone inhibitor, chemo-selectivity and species isolation by pheromone will be described. The modified triple bond migration and triethylamine liganded vinyl cuprate were applied for achiral pheromone synthesis in double bond formation. Some optically active pheromones and their stereoisomers were synthesized through chiral pool or asymmetric synthesis. Some examples of chiral recognition of insects towards their chiral pheromones will be discussed. A CaH2 and silica gel catalyzed Sharpless Expoxidation Reaction was found in shortening the reaction time.

【 授权许可】

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