Genotoxicity of plant extracts

Memórias do Instituto Oswaldo Cruz

Vera M. F. Vargas²  Régis R. Guidobono²  João A. P. Henriques¹ 

[1] ,Secretaria da Saúde do Meio Ambiente Departamento do Meio Ambiente Porto Alegre,Brasil

关键词: Ames test;    flovonoids;    tannins;    plant extracts;    Achyrocline satureoides;    Luehea divaricata;    Baccharis anomala;   

DOI  :  10.1590/S0074-02761991000600017

来源: SciELO

【 摘 要 】

Aqueous extracts of seven species used in Brazilian popular medicine (Achyrocline satureoides, Iodina rhombifolia, Desmodium incanum, Baccharis anomala, Tibouchina asperior, Luehea divaricata, Maytenus ilicifolia) were screened to the presence of mutagenic activity in the Ames test (Salmonella/microsome). Positive results were obtained for A. satureoides, B anomala and L. divaricata with microsomal activation. As shown elsewhere (Vargas et al., 1990) the metabolites of A. satureoides extract also show the capacity to induce prophage and/or SOS response in microscreen phage induction assay and SOS spot chromotest.

【 授权许可】

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