Aspergillus fumigatus fungus ball in hospitalized patients with chronic pulmonary disease: usefulness of double immunodiffusion test as a screening procedure

Memórias do Instituto Oswaldo Cruz

M. F. Ferreira-da-cruz²  B. Wanke¹  C. Pirmez¹  B. Galvão-castro¹ 

[1] ,Hospital Evandro ChagasRio de Janeiro,Brasil

关键词: aspergillosis;    fungus ball;    double immunodiffusion;    aspergilose;    bola fúngica;    imunodifusão dupla;   

DOI  :  10.1590/S0074-02761988000300013

来源: SciELO

【 摘 要 】

Double immunodiffusion (DID) was used as a screening test for the diagnosis of aspergillosis. Three hundred and fifty patients were tested, all of them referred from a specialized chest disease hospital and without a definitive etiological diagnosis. When DID was positive addtional information such as clinical history and radiographic findings were requested and also surgicalspecimens were obtained whenever possible. Specific precipitin hamds for Aspergillus fumigatus antigen were found in 29 (8.3%) of 350 patients sera. Nineteen (65.5%) of the 29 patients with positive serology were recognized as having a fungus ball by X-rays signs in 17 or by pathological examination in 2 or by both in 8 patients. This two-year prospective study has shown that pulmonary aspergillos is a considerable problem among patiens admitted to a Chest Diseases Hospital, especially in those with pulmonary cavities or bronchiectasis.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License