Cerebral calcifications and schizophreniform disorder

Jornal Brasileiro de Psiquiatria

Leonardo Fernandez Meyer²  Flávio Jozef¹  José Geraldo Vernet Taborda¹  Marco Antonio Alves Brasil²  Alexandre Martins Valença¹ 

[1] ,Universidade Federal do Rio de Janeiro Hospital Universitário Clementino Fraga Filho Rio de Janeiro RJ ,Brazil

关键词: Basal ganglia calcification;    organic psychosis;    Fahr's disease;    dementia;    schizophreniform disorder;    calcium and phosphorus metabolism disturbances;    hypoparathyroidism;    Calcificação dos gânglios da base;    psicose orgânica;    doença de Fahr;    demência;    transtorno esquizofreniforme;    distúrbios do metabolismo do cálcio e fósforo;    hipoparatireoidismo;   

DOI  :  10.1590/S0047-20852013000100011

来源: SciELO

【 摘 要 】

OBJECTIVES: Discuss pathophysiological aspects of cerebral calcifications (CC) and highlight its importance related to the occurrence of neuropsychiatric syndromes. METHOD: Single case report. RESULT: Man 52 years old, 20 years after going through a total thyroidectomy, starts showing behavioral disturbance (psychotic syndrome). He was diagnosed as schizophrenic (paranoid subtype) and submitted to outpatient psychiatric treatment. During a psychiatric admission to evaluate his progressive cognitive and motor deterioration, we identified a dementia syndrome and extensive cerebral calcifications, derived from iatrogenic hypoparathyroidism. CONCLUSION: The calcium and phosphorus disturbances, including hypoparathyroidism, are common causes of CC. Its symptoms can imitate psychiatric disorders and produce serious and permanent cognitive sequelae. The exclusion of organicity is mandatory in any psychiatric investigative diagnosis in order to avoid unfavorable outcomes, such as in the present case report.

【 授权许可】

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