Jornal Brasileiro de Psiquiatria | |
Cerebral perfusion and automated individual analysis using SPECT among an obsessive-compulsive population | |
Euclides Timóteo Da Rocha1  Carlos Alberto Buchpiguel2  Euripedes Constantino Miguel2  Stela Verzinhase Peres2  Geraldo Busatto Filho2  | |
[1] ,Fundação Pio XII Hospital de Câncer Department of Nuclear MedicineBarretos SP ,Brazil | |
关键词: Brain SPECT; SPM; OCD; individual analysis; SPECT cerebral; TOC; SPM; análise individual; | |
DOI : 10.1590/S0047-20852011000100001 | |
来源: SciELO | |
【 摘 要 】
OBJECTIVE: To make individual assessments using automated quantification methodology in order to screen for perfusion abnormalities in cerebral SPECT examinations among a sample of subjects with OCD. METHODS: Statistical parametric mapping (SPM) was used to compare 26 brain SPECT images from patients with OCD individually with an image bank of 32 normal subjects, using the statistical threshold of p < 0.05 (corrected for multiple comparisons at the level of individual voxels or clusters). The maps were analyzed, and regions presenting voxels that remained above this threshold were sought. RESULTS: Six patients from a sample of 26 OCD images showed abnormalities at cluster or voxel level, considering the criteria described above, which represented 23.07%. However, seven images from the normal group of 32 were also indicated as cases of perfusional abnormality, representing 21.8% of the sample. CONCLUSION: The automated quantification method was not considered to be a useful tool for clinical practice, for analyses complementary to visual inspection.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202005130040250ZK.pdf | 678KB | download |