Prevalence of Chagas disease in blood donors at the Uberaba Regional Blood Center, Brazil, from 1995 to 2009

Revista da Sociedade Brasileira de Medicina Tropical

Laryssa Manso De Lima²  Nathália Passos Alves¹  Valdirene De Fátima Barbosa¹  Gustavo Alves Pimenta¹  Helio Moraes-souza¹  Paulo Roberto Juliano Martins¹ 

[1] ,Universidade Federal do Triângulo MineiroUberaba MG

关键词: Chagas disease;    Transmission by transfusion;    Blood donors;    Serologic ineligibility;    Doença de Chagas;    Transmissão transfusional;    Doadores de sangue;    Inaptidão sorológica;   

DOI  :  10.1590/S0037-86822012000600013

来源: SciELO

【 摘 要 】

INTRODUCTION: A retrospective study was conducted to assess the occurrence of blood donations that were ineligible due to Chagas disease infection from 1995 to 2009 at the Uberaba Regional Blood Center (HRU), Brazil, verify the tendency of this ineligibility, and describe the epidemiologic profile of the donors. METHODS: Retrospective studies of serological ineligibility due to Chagas disease, statistical analysis by means of the chi-square test and odds ratio, study of the tendencies using a dispersion graph and the linear correlation coefficient (r) were performed. RESULTS: In the period under study, a 0.2% serum prevalence of ineligibility due to Chagas disease was found, with a significant drop in ineligible donations from 2001 to 2009. Among the serum positive-donors, there was a significant predominance among those aged 30 years or above and non-single individuals. CONCLUSIONS: The results show a rate of occurrence that is lower than that described in literature, as well as a progressive drop during the 15 years under assessment. Such results are a consequence of systematic combat of the vector since the 70s and the progressive and consistent increase of returning donors, resulting in a drop of the contamination risk factor by means of blood transfusion and in the improvement of the quality of hemotherapy practices in the HRU.

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