Autochthonous visceral leishmaniasis in Brasília, Federal District, Brazil

Revista da Sociedade Brasileira de Medicina Tropical

César Omar Carranza-tamayo²  Maria Do Socorro Laurentino De Carvalho¹  Angelika Bredt¹  Maria Isabel Rao Bofil¹  Rodrigo Menna Barreto Rodrigues¹  Ailton Domício Da Silva¹  Sandra Maria Felipe Coelho Cortez¹  Gustavo Adolfo Sierra Romero² 

[1] ,University of Brasilia Tropical Medicine Unit Brasília DF ,Brazil

关键词: Visceral leishmaniasis;    Autochthony;    Leishmania chagasi;    Leishmania infantum;    Lutzomyia longipalpis;    Leishmaniose visceral;    Autoctonia;    Leishmania chagasi;    Leishmania infantum;    Lutzomyia longipalpis;   

DOI  :  10.1590/S0037-86822010000400012

来源: SciELO

【 摘 要 】

INTRODUCTION: Visceral leishmaniasis is a public health threat in Brazil considering the high lethality rates and increasing geographical dispersion to large urban conglomerates over the past 25 years. This study aimed to confirm suspected autochthonous cases of visceral leishmaniasis reported from 2005 to 2009 among individuals living in Brasilia, Federal District. METHODS: A retrospective review of the surveillance data obtained on a regular basis and clinical records of the reported cases were performed in 2009. RESULTS: Data from entomological and canine surveys revealed the presence of both Lutzomyia longipalpis and positive serology for Leishmania in dogs within 19 of the 21 neighborhoods where human cases occurred since 2005. The review of surveillance data and medical records, together with the entomological and canine survey data, permitted confirmation of 21 autochthonous human cases in the Federal District. The disease predominantly affected children (12/21) and those from the Sobradinho region (16/21); the typical presentation of fever, hepatosplenomegaly and pancytopenia was observed in 67% of cases. Three deaths occurred during the study period. Leishmania (Leishmania) chagasi was successfully isolated from one human case and twelve canine cases. CONCLUSIONS: Visceral leishmaniasis should be considered endemic in Brasilia based on the documented epidemiological behavior herein described and the confirmed autochthony of human cases.

【 授权许可】

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