First occurrence of an autochthonous canine case of Leishmania (Leishmania) infantum chagasi in the municipality of Campinas, State of São Paulo, Brazil

Revista do Instituto de Medicina Tropical de São Paulo

Elisa San Martin Mouriz Savani²  Douglas Presotto¹  Thais Roberto¹  Maria Cecília Gibrail De Oliveira Camargo²  Sandra Regina Nicoletti D'auria²  Débora Veiga Sacramento¹ 

[1] ,Centro de Controle de Zoonoses do Município de São PauloSão Paulo SP ,Brazil

关键词: Visceral leishmaniasis;    PCR;    Epidemiology;    Dogs;    São Paulo;    Brazil;   

DOI  :  10.1590/S0036-46652011000400010

来源: SciELO

【 摘 要 】

An autochthonous case of visceral leishmaniasis is reported in a dog (Canis familiaris) as an apparently natural infection in a non-endemic area. DNA obtained from spleen and liver samples produced the expected fragment in a Leishmania-specific rDNA-based nested-PCR assay. The PCR product, a 490 bp fragment, was sequenced and the nucleotide sequence was identical to that of Leishmania (Leishmania) infantum chagasi. These results are surprising since no autochthonous human or canine cases of visceral leishmaniasis have ever been reported in this municipality. This case suggests that natural transmission of this disease is occurring in this area.

【 授权许可】

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