Molecular characterization of Cryptosporidium spp. from HIV infected patients from an urban area of Brazil

Revista do Instituto de Medicina Tropical de São Paulo

Patrícia De Lucca²  Elizabeth Natal De Gaspari¹  Lígia M. Bozzoli¹  Mikaela Renata Funada²  Sheila Oliveira De Souza Silva²  Wilma Iuliano¹  Rodrigo Martins Soares² 

[1],Universidade de São Paulo Faculdade de Medicina Veterinária e Zootecnia Departamento de Medicina Veterinária Preventiva e Saúde AnimalSP São Paulo ,Brazil

关键词: Cryptosporidium spp.;    Molecular characterization;    Human;    HIV;    Zoonosis;    Brazil;   

DOI  :  10.1590/S0036-46652009000600006

来源: SciELO

【 摘 要 】

Cryptosporidium spp. are important cause of enteric disease in humans, but may also infect animals. This study describes the relative frequency of several Cryptosporidium species found in human specimens from HIV infected patients in the São Paulo municipality obtained from January to July 2007. Sequence analysis of the products of nested-PCR based on small subunit rRNA and Cryptosporidium oocyst wall protein coding genes revealed 17 (63.0%) isolates of C. hominis, four (14.8%) C. parvum, five (18.5%) C. felis and one (3.7%) C. canis. These findings suggest that, in urban environments of Brazil, the cat adapted C. felis may play a potential role in the zoonotic transmission of cryptosporidiosis whereas the anthroponotic transmission of cryptosporidiosis caused by C. hominis seems to predominate.

【 授权许可】

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