Soft tissue abscess and lymphadenitis due to Mycobacterium avium Complex as an expression of immune reconstitution inflammatory syndrome after a second scheme of highly active antiretroviral therapy

Revista do Instituto de Medicina Tropical de São Paulo

Marcelo Corti²  María F. Villafañe²  Marta Ambroggi¹  Mirna Sawicki¹  Elisa Gancedo¹ 

[1] ,Infectious Diseases F. J. Muñiz Hospital Division of HIV/AIDS Buenos Aires,Argentina

关键词: HAART;    Immune reconstitution inflammatory syndrome;    Mycobacterium avium complex;   

DOI  :  10.1590/S0036-46652007000400015

来源: SciELO

【 摘 要 】

Immune reconstitution inflammatory syndrome (IRIS) is an atypical and unexpected reaction related to highly active antiretroviral therapy (HAART) in human immunodeficiency virus (HIV) infected patients. IRIS includes an atypical response to an opportunistic pathogen (generally Mycobacterium tuberculosis, Mycobacterium avium complex, cytomegalovirus and herpes varicella-zoster), in patients responding to HAART with a reduction of plasma viral load and evidence of immune restoration based on increase of CD4+ T-cell count. We reported a case of a patient with AIDS which, after a first failure of HAART, developed a subcutaneous abscess and supraclavicular lymphadenitis as an expression of IRIS due to Mycobacterium avium complex after starting a second scheme of HAART.

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