Mass treatment for intestinal helminthisis control in an Amazonian endemic area in Brazil

Revista do Instituto de Medicina Tropical de São Paulo

Márcio Neves Bóia²  Filipe Anibal Carvalho- Costa¹  Fernando Campos Sodré¹  Walter A. Eyer-silva¹  Cristiane Cruz Lamas¹  Marcelo Rosadinski Lyra¹  Vitor Laerte Pinto Júnior¹  João Paulo Cantalice Filho¹  Ana Lucia L. Oliveira¹  Liège M. Abreu Carvalho¹  Julise B. Gross¹  Ana Lucia S. Sousa¹  Teruo Ito De Moraes¹  Elkin Hernán Bermudez-aza¹  Ezequias Baptista Martins¹  José Rodrigues Coura² 

[1] ,Fiocruz IOC Departamento de Medicina Tropical RJ ,Brasil

关键词: Intestinal helminthiasis;    Mass Treatment;    Control;    Amazon;   

DOI  :  10.1590/S0036-46652006000400003

来源: SciELO

【 摘 要 】

The objective of the present study was to estimate the prevalence of soil-transmitted helminthiasis and evaluate the sanitary conditions and the role of a mass treatment campaign for control of these infections in Santa Isabel do Rio Negro. A cross-sectional survey was carried out in 2002, to obtain data related to the sanitary conditions of the population and fecal samples for parasitological examination in 308 individuals, followed by a mass treatment with albendazole or mebendazole with coverage of 83% of the city population in 2003. A new survey was carried out in 2004, involving 214 individuals, for comparison of the prevalences of intestinal parasitosis before and after the mass treatment. The prevalences of ascariasis, trichuriasis and hookworm infection were 48%; 27% and 21% respectively in 2002. There was a significant decrease for the frequency of infections by Ascaris lumbricoides (p < 0.05; OR / 95% CI = 0.44 / 0.30 - 0.65), Trichuris trichiura (p < 0.05; OR / 95% CI = 0.37 / 0.22 - 0.62), hookworm (p < 0.05; OR / 95% CI = 0.03 / 0.01 - 0.15) and helminth poliparasitism (p < 0.05; OR / 95% CI = 0.16 / 0.08 - 0.32). It was also noticed a decrease of prevalence of infection by Entamoeba histolytica / dispar (p < 0.05; OR / 95% CI = 0.30 / 0.19 - 0.49) and non-pathogenic amoebas. It was inferred that a mass treatment can contribute to the control of soil-transmitted helminthiasis as a practicable short-dated measure. However, governmental plans for public health, education and urban infrastructure are essential for the sustained reduction of prevalences of those infections.

【 授权许可】

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