Genetic relationships among serogroup B: serotype 4 Neisseria meningitidis strains

Revista do Instituto de Medicina Tropical de São Paulo

Ana Paula S. Lemos²  Claudio T. Sacchi²  Maria V. Paiva²  Teresa I. Yara²  Carmo Elias A. Melles²  Leonard W. Mayer¹ 

[1] ,Adolfo Lutz Institute Bacteriology Department Division of Medical BiologySão Paulo SP ,Brazil

关键词: Neisseria meningitidis;    Serogroup B;    Serotype 4;    Ribotyping;    Strain differentiation;   

DOI  :  10.1590/S0036-46652001000300001

来源: SciELO

【 摘 要 】

We compared the results obtained by serotyping of PorB epitopes using an expanded panel of monoclonal antibodies (mAb) including mAb 7 and mAb 10, with results obtained by RFLP of rRNA genes (ribotyping). The purpose of this study was to assess the correlation between phenotypic- and genotypic- methods for typing N. meningitidis. The ribotypes obtained using ClaI or EcoRV endonucleases grouped the strains in seven and two different patterns, respectively. This additional characterization of PorB epitopes improved the correlation between these two methods of typing N. meningitidis.

【 授权许可】

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