Thiamphenicol in the treatment of chancroid. A study of 1,128 cases

Revista do Instituto de Medicina Tropical de São Paulo

Walter Belda Junior²  Luis Fernando De Goes Siqueira¹  Luiz Jorge Fagundes¹ 

[1] ,University of S. Paulo Faculty of Medicine Department of DermatologyS. Paulo SP ,Brasil

关键词: Thiamphenicol;    Chancroid;    Therapy;   

DOI  :  10.1590/S0036-46652000000300004

来源: SciELO

【 摘 要 】

Thiamphenicol, an aminic derivate of hydrocarbilsulfonil propandiol, was used for the treatment of 1,171 chancroid bearing patients. Each patient was medicated with 5.0 g of granulated thiamphenicol, orally, in a single dose, and was reevaluated 3, 7 and 10 days after the treatment. Ten patients (0.89%) did not respond to the proposed treatment. 133 patients presented healed ulcers after 3 days of treatment, 976 patients healed chancres on the seventh day after the treatment, and 39 patients took 10 days to present healed chancres. The results of this study indicate that the rate of patients that were cured, the low incidence of side effects, and the practicality of administration make of thiamphenicol an excellent choice for the treatment of chancroid.

【 授权许可】

CC BY-NC   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License