Serum phenylalanine in preterm newborns fed different diets of human milk,

Jornal de Pediatria

Débora M. Thomaz¹  Paula O. Serafin¹  Durval B. Palhares¹  Luciana V.m. Tavares¹  Thayana R.s. Grance¹ 

关键词: Serum phenylalanine;    Human milk;    Human milk fortifier;    Banked human milk;    Preterm newborns;    Fenilalanina plasmática;    Leite humano;    Aditivo para leite humano;    Leite humano de banco;    Recém-nascido pré-termo;   

DOI  :  10.1016/j.jped.2014.02.003

来源: SciELO

【 摘 要 】

Objective:To evaluate phenylalanine plasma profile in preterm newborns fed different human milk diets.Methods:Twenty-four very-low weight preterm newborns were distributed randomly in three groups with different feeding types: Group I: banked human milk plus 5% commercial fortifier with bovine protein, Group II: banked human milk plus evaporated fortifier derived from modified human milk, Group III: banked human milk plus lyophilized fortifier derived from modified human milk. The newborns received the group diet when full diet was attained at 15 ± 2 days. Plasma amino acid analysis was performedon the first and last day of feeding. Comparison among groups was performed by statistical tests: one way ANOVA with Tukey's post-test using SPSS software, version 20.0 (IBM Corp, NY, USA), considering a significance level of 5%.Results:Phenylalanine levels in the first and second analysis were, respectively, in Group I: 11.9 ± 1.22 and 29.72 ± 0.73; in Group II: 11.72 ± 1.04 and 13.44 ± 0.61; and in Group III: 11.3 ± 1.18 and 15.42 ± 0.83 μmol/L.Conclusion:The observed results demonstrated that human milk with fortifiers derived from human milk acted as a good substratum for preterm infant feeding both in the evaporated or the lyophilized form, without significant increases in plasma phenylalanine levels in comparison to human milk with commercial fortifier.

【 授权许可】

CC BY-NC-ND   
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