Why this is not multiple sclerosis: a case based approach

Arquivos de Neuro-Psiquiatria

Zaira Fernanda Martinho Nicolau¹  Enedina Maria Lobato De Oliveira¹  Denis Bernardi Bichuetti¹ 

关键词: multiple sclerosis;    diagnosis;    clinical;    MRI red flags;    esclerose múltipla;    diagnóstico;    clínico;    ressonância magnética;   

DOI  :  10.1590/0004-282X20150163

来源: SciELO

【 摘 要 】

ObjectiveTo present a case series of patients previously diagnosed as multiple sclerosis (MS) which were later confirmed as an alternative diagnosis, and describe the clinical and paraclinical signs that led to this change.MethodNine patients are described. We reviewed the patient’s clinical chart, magnetic resonance images (MRI) and cerebrospinal fluid.ResultsThere was a mean of three typical symptoms of MS and four clinical red flags per patient. MRI red flags were found in 88,9% of all referrals, with a mean of 3 encountered per patient.ConclusionWe identified that, not only the misdiagnosed patients did not fulfill MS diagnosis criteria, but also how the described red flags are a useful tool in the differentiation of MS from other diseases. This data is important for guiding future diagnosis, especially for general clinicians and neurologists, which directly interfere with the patient’s management, treatment, prognosis and quality of life.

【 授权许可】

CC BY   
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