Gross-total resection of temporal low grade gliomas is a critically important factor in achieving seizure-freedom

Arquivos de Neuro-Psiquiatria

Lucas Crociati Meguins¹  Rodrigo Antônio Rocha Da Cruz Adry¹  Sebastião Carlos Da Silva Júnior¹  Carlos Umberto Pereira¹  Jean Gonçalves De Oliveira¹  Dionei Freitas De Morais¹  Gerardo Maria De Araújo Filho¹  Lúcia Helena Neves Marques¹ 

关键词: temporal low-grade gliomas;    intractable epilepsy;    long-term seizure outcome;    glioma temporal de baixo grau;    epilepsia de difícil controle;    controle das crises;   

DOI  :  10.1590/0004-282X20150141

来源: SciELO

【 摘 要 】

Objective To present a surgical series of patients with low grade temporal gliomas causing intractable epilepsy, focusing on long-term seizure outcome.Method A retrospective study was conducted with patients with temporal low-grade gliomas (LGG).Results Sixty five patients with were operated in our institution. Males were more affected than females and the mean age at surgery was 32.3 ± 8.4 (9-68 years). The mean age at seizure onset was 25.7 ± 9.2 (11-66 years). Seizure outcome was classified according with Engel classification. After one year of follow up, forty two patients (64.6%) were Engel I; seventeen (26.2%) Engel II; four (6.2%) Engel III and two (3.1%) Engel IV. Statistically significant difference in seizure outcome was obtained when comparing the extension of resection. Engel I was observed in 39 patients (69.6%) with total resection and in only 3 (33.3%) patients with partial resection.Conclusion Gross-total resection of temporal LGGs is a critically important factor in achieving seizure-freedom.

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