Survival analysis in patients with metastatic spinal disease: the influence of surgery, histology, clinical and neurologic status

Arquivos de Neuro-Psiquiatria

Matheus Fernandes De Oliveira¹  Jose Marcus Rotta¹  Ricardo Vieira Botelho¹ 

关键词: neoplasm metastasis;    spinal diseases;    prognosis;    metástases;    doenças espinhais;    prognóstico;   

DOI  :  10.1590/0004-282X20150003

来源: SciELO

【 摘 要 】

Spine is the most common site for skeletal metastasis in patients with malignancy. Vertebral involvement quantification, neurological status, general health status and primary tumor histology are factors to set surgical planning and therapeutic targets. We evaluated the impact of general clinical and neurological status, histologic type and surgery in survival. Method : The study sample consisted of consecutive patients admitted from July 2010 to January 2013 for treatment. Results : Sixty eight patients were evaluated. 23 were female and 45 were male. Main primary neoplasic sites were: breast, prostate, lung/pleura and linfoproliferative. Thirty three out of 68 received surgical treatment, 2 received percutaneous biopsy and 33 had nonsurgical treatment. Survival : Log Rank curves revealed no statistical significant difference according to histological type, surgical approach and Frankel Score. Karnofsky Score was statistically different. Conclusion : Histological type and clinical status were statistically associated with life expectancy in vertebral metastatic disease.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License