Visual evoked potentials show strong positive association with intracranial pressure in patients with cryptococcal meningitis

Arquivos de Neuro-Psiquiatria

Marcelo Adriano Da Cunha Silva Vieira¹  Maria Do Amparo Salmito Cavalcanti¹  Dorcas Lamounier Costa¹  Kelsen Dantas Eulálio¹  Otoni Cardoso Do Vale¹  Chrystiany Placido De Brito Vieira¹  Carlos Henrique Nery Costa¹ 

关键词: visual evoked potentials;    intracranial pressure;    cryptococcal meningitis;    potenciais evocados visuais;    pressão intracraniana;    meningite criptocócica;   

DOI  :  10.1590/0004-282X20150002

来源: SciELO

【 摘 要 】

Objective : To verify the relationship between intracranial pressure and flash visual evoked potentials (F-VEP) in patients with cryptococcal meningitis. Method The sample included adults diagnosed with cryptococcal meningitis admitted at a reference hospital for infectious diseases. The patients were subjected to F-VEP tests shortly before lumbar puncture. The Pearson’s linear correlation coefficient was calculated and the linear regression analysis was performed. Results : Eighteen individuals were subjected to a total of 69 lumbar punctures preceded by F-VEP tests. At the first lumbar puncture performed in each patient, N2 latency exhibited a strong positive correlation with intracranial pressure (r = 0.83; CI = 0.60 - 0.94; p < 0.0001). The direction of this relationship was maintained in subsequent punctures. Conclusion : The intracranial pressure measured by spinal tap manometry showed strong positive association with the N2 latency F-VEP in patients with cryptococcal meningitis.

【 授权许可】

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