Autonomic evaluation of hepatitis C virus infectedpatients

Arquivos de Neuro-Psiquiatria

Bruno Mattos Coutinho²  Eliane Bordalo²  Osvaldo J. M. Nascimento¹ 

[1] ,UPC Department of Internal Medicine and Neuro Rio de Janeiro RJ ,Brazil

关键词: hepatitis C;    dysautonomia;    small-fiber polyneuropathy;    hepatite C;    disautonomia;    polineuropatia de fibras finas;   

DOI  :  10.1590/0004-282X20130074

来源: SciELO

【 摘 要 】

There are few studies reporting the association between hepatitis C virus (HCV)infection and disautonomia. We have evaluated the autonomic cardiovascular functionin 12 patients with sensory small-fiber polyneuropathy infected by HCV. The mean agewas 49±13 years old. The mean infection time was 9.6 years in six (50%) patients.Thermal and pinprick hypoesthesia was observed in distal legs in all patients.Autonomic symptoms were referred by eight (66.7%) patients. Among patients withabnormal autonomic cardiovascular test, five (41.7%) showed abnormal results in twoor more tests. Valsalva maneuver was abnormal in seven (58.3%) patients. We canconsider that there is an association of both parasympathetic and sympatheticefferent cardiovascular dysfunction in this group of patients.

【 授权许可】

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