Mortality is higher in patients with leptomeningeal metastasis in spinal cord tumors

Arquivos de Neuro-Psiquiatria

Ricardo De Amoreira Gepp¹  José Mauro Cardoso Couto¹  Maria Dorvalina Da Silva¹  Marco Rolando Sainz Quiroga¹ 

[1] ,SARAH Network of Rehabilitation HospitalsBrasília DF ,Brazil

关键词: neoplasm metastasis;    spinal cord;    neoplasms;    metástase neoplásica;    medula espinhal;    neoplasias;   

DOI  :  10.1590/S0004-282X2012005000019

来源: SciELO

【 摘 要 】

Spinal cord tumors are a rare neoplasm of the central nervous system (CNS). The occurrence of metastases is related to poor prognosis. The authors analyzed one series of metastasis cases and their associated mortality. METHODS: Clinical characteristics were studied in six patients with intramedullary tumors with metastases in a series of 71 surgical cases. RESULTS: Five patients had ependymomas of which two were WHO grade III. The patient with astrocytoma had a grade II histopathological classification. Two patients required shunts for hydrocephalus. The survival curve showed a higher mortality than the general group of patients with no metastases in the CNS (p<0.0001). CONCLUSION: Mortality is elevated in patients with metastasis and greater than in patients with only primary lesions. The ependymomas, regardless of their degree of anaplasia, are more likely to cause metastasis than spinal cord astrocytomas.

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