Neurological symptoms and signs in HTLV-1 patients with overactive bladder syndrome

Arquivos de Neuro-Psiquiatria

Davi Tanajura Costa²  André Luiz Muniz Alves Dos Santos²  Néviton Matos De Castro²  Isadora Cristina De Siqueira²  Edgar Marcelino De Carvalho Filho²  Marshall Jay Glesby¹ 

[1] ,Bahia Federal University Immunology Department Salvador BA ,Brazil

关键词: spinal cord diseases;    urinary bladder neurogenic;    tropical spastic paraparesis;    myelitis;    doenças da medula espinal;    bexiga urinária neurogênica;    paraparesia espástica tropical;    mielite;   

DOI  :  10.1590/S0004-282X2012000400005

来源: SciELO

【 摘 要 】

OBJECTIVE: To compare neurological symptoms and signs in HTLV-1 asymptomatic carriers and HTLV-1 patients with overactive bladder (OB) syndrome. METHODS: We studied 102 HTLV-1 positive individuals without HAM/TSP (HTLV-1 associated myelopathy/tropical spastic paraparesis) divided into two groups according to the presence or absence of OB syndrome. Clinical interview, neurological exam and proviral load was performed in all patients. RESULTS AND CONCLUSIONS: Individuals with OB were more commonly female (84.3 vs. 60.8% of asymptomatics, p=0.01). The prevalence of neurological complaints was higher in OB group, especially hand or foot numbness and arm or leg weakness. There was no difference between the groups in neurological strength and reflexes. Weakness complaint remained strongly associated with OB in multivariate logistic regression analysis adjusting for sex and age [adjusted odds ratio and 95%CI 3.59 (1.45-8.88) in arms and 6.68 (2.63-16.93) in legs]. Proviral load was also different between the two groups with higher level on OB individuals.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License