Enterovirus and herpesviridae family as etiologic agents of lymphomonocytary meningitis, Southern Brazil

Arquivos de Neuro-Psiquiatria

Luine Rosele Renaud Vidal²  Sérgio Monteiro De Almeida¹  Iara José De Messias-reason¹  Meri Bordignon Nogueira¹  Maria Do Carmo Debur¹  Luís Felipe Cavalli Pessa¹  Luciane Aparecida Pereira¹  Indianara Rotta¹  Gislene Reche De Almeida Takahashi¹  Clyete Santos Da Silveira¹  Josianne Maria Reimann Araújo¹  Sonia Mara Raboni¹ 

[1] ,Universidade Federal do Paraná Hospital de Clínicas Virology LaboratoryCuritiba PR ,Brazil

关键词: aseptic meningitis;    lymphocytic meningitis;    lymphomonocytary meningitis;    cerebrospinal fluid;    central nervous system;    enterovirus;    herpesvirus;    meningite asséptica;    meningite linfocítica;    meningite linfomonocitária;    líquido cefalorraquidiano;    sistema nervoso central;    enterovirus;    herpesvirus;   

DOI  :  10.1590/S0004-282X2011000400013

来源: SciELO

【 摘 要 】

Viral meningitis is a common infectious disease of the central nervous system (CNS) that occurs worldwide. The aim of this study was to identify the etiologic agent of lymphomonocytary meningitis in Curitiba, PR, Brazil. During the period of July 2005 to December 2006, 460 cerebrospinal fluid (CSF) samples with lymphomonocytary meningitis were analyzed by PCR methodologies. Fifty nine (12.8%) samples were positive. Enteroviruses was present in 49 (83%) samples and herpes virus family in 10 (17%), of these 6 (10%) herpes simplex virus, 1 (2%) Epstein Barr virus, 2 (3%) human herpes virus type 6 and 1 (2%) mixed infection of enterovirus and Epstein Barr virus. As conclusion enterovirus was the most frequent virus, with circulation during summer and was observed with higher frequency between 4 to 17 years of age. PCR methodology is an important method for rapid detection of RNA enterovirus and DNA herpesvirus in CSF.

【 授权许可】

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