Extraneural metastases in medulloblastoma

Arquivos de Neuro-Psiquiatria

V M F Muoio²  S O Shinjo¹  H Matushita¹  S Rosemberg¹  M J Teixeira¹  S K N Marie² 

[1] ,University of São Paulo Medicine School Neurology DepartmentSão Paulo SP ,Brazil

关键词: medulloblastoma;    metastasis;    extraneural;    medulloblastoma;    metastases;    extraneural;   

DOI  :  10.1590/S0004-282X2011000300012

来源: SciELO

【 摘 要 】

Medulloblastoma is the most common childhood malignant tumor of central nervous system, but it may also occur in adults. It presents high invasive growth with spreading of tumor cells into the leptomeningeal space along the neuroaxis early in the course of the disease. Extraneural metastases are rare but frequently lethal, occurring only in 1 to 5% of patients, and are related, in the most of cases, to the presence of ventriculoperitoneal shunt. Here we characterize the clinical profile of five cases of medulloblastoma with systemic spreading of tumor cells, also comparing them to cases already described in the literature.

【 授权许可】

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