期刊论文详细信息
Arquivos de Neuro-Psiquiatria
Malformations of cortical development: current concepts and advanced neuroimaging review
Celi Santos Andrade2  Claudia Da Costa Leite1 
[1] ,University of São Paulo School of Medicine Radiology DepartmentSão Paulo,Brazil
关键词: malformations of cortical development;    epilepsy;    magnetic resonance imaging;    diagnostic imaging;    malformações do desenvolvimento cortical;    epilepsia;    imagem por ressonância magnética;    diagnóstico por imagem;   
DOI  :  10.1590/S0004-282X2011000100024
来源: SciELO
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【 摘 要 】

Malformations of cortical development (MCD) result from disruptions in the complex process of the human brain cortex formation and are highly associated to severe epilepsy, neurodevelopmental delay and motor dysfunction. Nowadays, magnetic resonance imaging (MRI) is the cornerstone of the work-up of patients with epilepsy and modern advanced imaging techniques have improved not only our ability to detect and characterize cortical malformations, but also in identifying associated functional abnormalities that are far beyond the structural visualized lesions. Herein, we address the most currently used classifications of MCD and make a concise review of the embryological process of cortical development. Our main goal is to summarize recent advances and new trends in diagnostic imaging techniques concerning MCD. Thereafter, follows a brief discussion of specific disorders and their radiological features.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License

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