Arquivos de Neuro-Psiquiatria | |
Progressive supranuclear palsy: new concepts | |
Orlando Graziani Povoas Barsottini1  André Carvalho Felício1  Camila Catherine Henriques De Aquino1  José Luiz Pedroso1  | |
[1] ,Federal University of São Paulo Department of Neurology and Neurosurgery São Paulo SP ,Brazil | |
关键词: progressive supranuclear palsy; atypical parkinsonism; tauopathy; paralisia supranuclear progressiva; parkinsonismo atípico; taupatias; | |
DOI : 10.1590/S0004-282X2010000600020 | |
来源: SciELO | |
![]() |
【 摘 要 】
Progressive supranuclear palsy (PSP) is a distinctive form of neurodegenerative disease which affects the brainstem and basal ganglia. Patients present supranuclear ophthalmoplegia, postural instability and mild dementia. PSP is defined neuropathologically by the accumulation of neurofibrillary tangles in the subthalamic nucleus, pallidum, red nucleus, substantia nigra, striatum, pontine tegmentum, oculomotor nucleus, medulla and dentate nucleus. Over the last decade many lines of investigations have helped refine PSP in many aspects and it is the purpose of this review to help neurologists identify PSP, to better understand its pathophysiology and to provide a more focused, symptom-based treatment approach.
【 授权许可】
CC BY
All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License
【 预 览 】
Files | Size | Format | View |
---|---|---|---|
RO202005130010851ZK.pdf | 684KB | ![]() |