Endoscopic endonasal transsphenoidal approach for pituitary adenomas: technical aspects and report of casuistic

Arquivos de Neuro-Psiquiatria

Américo Rubens Leite Dos Santos²  Roberto Monteiro Fonseca Neto²  José Carlos Esteves Veiga²  José Viana Jr¹  Nilza Maria Scaliassi¹  Carmen Lúcia Penteado Lancellotti¹  Paulo Roberto Lazarini¹ 

[1] ,Santa Casa de São Paulo Faculdade de Ciências Médicas Department of SurgerySão Paulo SP ,Brazil

关键词: endoscopy;    pituitary;    nasal;    surgery;    endoscopia;    hipófise;    nasal;    cirurgia;   

DOI  :  10.1590/S0004-282X2010000400024

来源: SciELO

【 摘 要 】

OBJECTIVE: Analyse technical aspects, effectiveness and morbidity of the endoscopic endonasal transphenoidal approach for pituitary adenomas. METHOD: From January 2005 to September 2008, 30 consecutive patients underwent endoscopic endonasal resection of pituitary adenomas with a follow up from 3 to 36 months. Their medical charts were retrospectively analysed. RESULTS: There were 18 women and 12 men, mean age 44 years (range 17-65 yr). Among the 30 patients, 23 had macroadenomas and 7 microadenomas. Twelve patients had non-functioning tumors, 9 had ACTH-secreting tumors, 8 had GH-secreting tumors and 1 prolactinoma. Complete resection and hormonal control was achieved in all microadenomas. Macroadenomas were completely removed in 6 patients, subtotal resection in 6 and partial resection in 11. Three patients had diabetes insipidus and 5 had CSF leaks treated with lumbar drainage. CONCLUSION: The endonasal endoscopic approach for pituitary tumors is effective and has low morbidity.

【 授权许可】

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