Auditory evoked potentials and multiple sclerosis

Arquivos de Neuro-Psiquiatria

Carla Gentile Matas¹  Sandro Luiz De Andrade Matas²  Caroline Rondina Salzano De Oliveira²  Isabela Crivellaro Gonçalves² 

[1] ,FMUSP Speech Pathology and Audiology Course

关键词: auditory evoked potentials;    auditory brain stem evoked potentials;    P300 event-related potentials;    multiple sclerosis;    potenciais evocados auditivos;    potenciais evocados auditivos do tronco encefálico;    potencial evocado P300;    esclerose múltipla;   

DOI  :  10.1590/S0004-282X2010000400010

来源: SciELO

【 摘 要 】

Multiple sclerosis (MS) is an inflammatory, demyelinating disease that can affect several areas of the central nervous system. Damage along the auditory pathway can alter its integrity significantly. Therefore, it is important to investigate the auditory pathway, from the brainstem to the cortex, in individuals with MS. OBJECTIVE: The aim of this study was to characterize auditory evoked potentials in adults with MS of the remittent-recurrent type. METHOD: The study comprised 25 individuals with MS, between 25 and 55 years, and 25 age- and gender-matched healthy controls (research and control groups). Subjects underwent audiological and electrophysiological evaluations. RESULTS: Statistically significant differences were observed between the groups regarding the results of the auditory brainstem response and the latency of the Na and P300 waves. CONCLUSION: Individuals with MS present abnormalities in auditory evoked potentials indicating dysfunction of different regions of the central auditory nervous system.

【 授权许可】

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