Electrophysiological and auditory behavioral evaluation of individuals with left temporal lobe epilepsy

Arquivos de Neuro-Psiquiatria

Caroline Nunes Rocha²  Carmen Silvia Molleis Galego Miziara¹  Maria Luiza Giraldes De Manreza¹  Eliane Schochat¹ 

[1] ,University of São Paulo School of Medicine

关键词: epilepsy;    event-related potentials P300;    mesial temporal sclerosis;    epilepsia;    potencial evocado P300;    esclerose mesial temporal;   

DOI  :  10.1590/S0004-282X2010000100005

来源: SciELO

【 摘 要 】

The purpose of this study was to determine the repercussions of left temporal lobe epilepsy (TLE) for subjects with left mesial temporal sclerosis (LMTS) in relation to the behavioral test-Dichotic Digits Test (DDT), event-related potential (P300), and to compare the two temporal lobes in terms of P300 latency and amplitude. We studied 12 subjects with LMTS and 12 control subjects without LMTS. Relationships between P300 latency and P300 amplitude at sites C3A1,C3A2,C4A1, and C4A2, together with DDT results, were studied in inter-and intra-group analyses. On the DDT, subjects with LMTS performed poorly in comparison to controls. This difference was statistically significant for both ears. The P300 was absent in 6 individuals with LMTS. Regarding P300 latency and amplitude, as a group, LMTS subjects presented trend toward greater P300 latency and lower P300 amplitude at all positions in relation to controls, difference being statistically significant for C3A1 and C4A2. However, it was not possible to determine laterality effect of P300 between affected and unaffected hemispheres.

【 授权许可】

CC BY   
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