期刊论文详细信息
Arquivos de Neuro-Psiquiatria
Pain in tropical spastic paraparesis/HTLV-I associated myelopathy patients
Carlos Maurício De Castro-costa2  Abelardo De Queiroz Campos Araújo1  Carlos C. Câmara2  Ayrton S. Ferreira2  Terezinha De Jesus T. Santos2  Samuel Bovy De Castro-costa2  Raimundo Neudson M. Alcântara2  Graham P. Taylor1 
[1] ,Universidade Federal do Ceará Instituto de Biomedicina Departamento de Fisiologia e FarmacologiaFortaleza CE ,Brazil
关键词: TSP/HAM;    HTLV-I;    pain;    inflammatory nociceptive and neuropathic;    cytokines;    PET/MAH;    HTLV-I;    dor;    nociceptiva inflamatória e neuropática;    citocinas;   
DOI  :  10.1590/S0004-282X2009000500016
来源: SciELO
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【 摘 要 】

OBJECTIVE: Tropical Spastic Paraparesis/HTLV-I Associated Myelopathy (TSP/HAM) is a chronic myelopathy, and pain has been mentioned as a frequent sensory symptom in this condition. The authors aimed at analyzing this symptom in a TSP/HAM patients series. METHOD: For this, 46 patients were analyzed considering demographic and clinical characteristics and complaint of pain as to verbal description, time of onset and classification, correlated with the degree of motor disability and type of pain. RESULTS: Among the 46 TSP/HAM patients, 28 (60.8%) complained of pain, predominant in the early phase of the disease. Most of the patients exhibited neuropathic characteristics of pain, correlated with increased motor disability. CONCLUSION: Pain in TSP/HAM patients is a frequent and early symptom, and the neuropathic type is predominant (57.1%) and paralleled with increased incapacitation. The pathogenic involvement of cytokines may possibly be involved in the meaning of this symptom in this condition.

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