Pregnancy and multiple sclerosis: the initial results from a Brazilian database

Arquivos de Neuro-Psiquiatria

Yara Dadalti Fragoso²  Alessandro Finkelsztejn¹  Elizabeth Regina Comini-frota¹  Paulo Diniz Da Gama¹  Ansderson Kuntz Grzesiuk¹  Jussara Mathias Netto Khouri¹  Soniza Vieira Alves-leon¹  Rogério De Rizo Morales¹  Marco Aurélio Lana-peixoto¹  Cristiane Franklin Da Rocha¹ 

[1] ,Universidade Metropolitana de SantosSantos SP ,Brazil

关键词: multiple sclerosis;    pregnancy;    prematurity;    low birth weight;    obstetric complications;    interferon beta;    glatiramer acetate;    esclerose múltipla;    gravidez;    prematuridade;    baixo peso;    complicações obstétricas;    interferon beta;    acetato de glatirâmer;   

DOI  :  10.1590/S0004-282X2009000400015

来源: SciELO

【 摘 要 】

PURPOSE: Pregnancy management poses an extra challenge to physicians and their multiple sclerosis (MS) patients. There are few papers reporting databases on the subject. METHOD: Brazilian database from nine MS clinical and research units, with complete data on 47 pregnant women (49 pregnancies). RESULTS: Despite relatively high exposure to MS medications, no birth defects were reported. Low birth weight and prematurity were similar to those for developing countries. Three complications may have been associated with these medications, while three others were considered to be of purely obstetric nature. CONCLUSION: Our results confirm previous findings on lower relapse rate during pregnancy and add to the present literature informing on data related to drug exposure.

【 授权许可】

CC BY   
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