Risk factors of heterotopic ossification in traumatic spinal cord injury

Arquivos de Neuro-Psiquiatria

Cláudia Virgínia C. Coelho²  Paulo Sergio S. Beraldo¹ 

[1] ,Hospital SARAH CentroBrasília DF ,Brazil

关键词: heterotopic ossification;    spinal cord injuries;    pressure ulcer;    muscle spasticity;    risk factors;    multivariate analysis;    ossificação heterotópica;    traumatismos da medula espinal;    úlcera de pressão;    espasticidade muscular;    fatores de risco;    análise multivariada;   

DOI  :  10.1590/S0004-282X2009000300002

来源: SciELO

【 摘 要 】

OBJECTIVE: Heterotopic ossification (HO) is a complication of the spinal cord injury (SCI). It can result in anchylosis, harming the rehabilitation and quality of life. Previous publications had not elucidated the relation between possible independent variables, the aim of this study. METHOD: From 230 patients with SCI, admitted in 1998 at Hospital SARAH Brasilia, 33 with HO (14.3%; CI95% 10.1-19.6) were compared with 33 controls. The risk factors had been tested in bivariate analysis and in a model of logistic regression. RESULTS: Spasticity (odds ratio=3.8; CI95% 1.15-12.30), number of pressure ulcers (2.1; CI95% 1.08-3.89) and time lapsed since the injury (1.1; CI95% 1.02-1.24) were independently associated with HO. There was a confounder effect among these variables, without interaction. CONCLUSION: Spasticity, pressure ulcer and time of injury are associated with HO in spinal cord injury. The first two factors can be prevented and treatable.

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