Application of magnetic resonance spectroscopy in the differentiation of high-grade brain neoplasm and inflammatory brain lesions

Arquivos de Neuro-Psiquiatria

José Roberto Lopes Ferraz-filho²  Pedro Vieira Santana-netto¹  Jose Alves Rocha-filho¹  Aline Sgnolf¹  Fernando Mauad¹  Rafael Angelo Sanches¹ 

[1] ,FAMERP Medical School Department, Doctor's candidate Health Sciences Program São José do Rio Preto SP ,Brazil

关键词: magnetic resonance image;    spectroscopy;    brain;    neoplasm;    inflammatory lesion;    ressonância magnética;    espectroscopia;    encéfalo;    neoplasia;    lesão inflamatória;   

DOI  :  10.1590/S0004-282X2009000200014

来源: SciELO

【 摘 要 】

This study aims at evaluating the application of magnetic resonance spectroscopy (MRS) in the differential diagnosis of brain tumors and inflammatory brain lesions. The examinations of 81 individuals, who performed brain MRS and were retrospectively analyzed. The patients with ages between 10 and 80 years old, were divided into two groups. Group A consisted of 42 individuals with diagnoses of cerebral toxoplasmosis and Group B was formed of 39 individuals with diagnosis of glial neoplasms. On analyzing the ROC curve, the discriminatory boundary for the Cho/Cr ratio between inflammatory lesions and tumors was 1.97 and for the NAA/Cr ratio it was 1.12. RMS is an important method useful in the distinction of inflammatory brain lesions and high-degree tumors when the Cho/Cr ratio is greater than 1.97 and the NAA/Cr ratio is less than 1.12. And so this method is important in the planning of treatment and monitoring of the therapeutic efficiency.

【 授权许可】

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