Is there something special about cardiovascular abnormalities and sudden unexpected death in epilepsy among patients with chronic renal insufficiency in regular hemodialysis program?

Arquivos de Neuro-Psiquiatria

Rui A. Gomes²  Silvana Kesrouani¹  Jenner Cruz¹  Alexandre L. Silva¹  Tânia M.g. Henriques¹  Marly De Albuquerque²  Ricardo M. Arida¹  Eliza Y.f. Sonoda²  Roberta M. Cysneiros¹  Vera C. Terra¹  Carla A. Scorza²  Esper A. Cavalheiro²  Fulvio A. Scorza² 

[1] ,Universidade Federal de São Paulo Escola Paulista de Medicina São Paulo SP ,Brazil

关键词: epilepsy;    sudden death;    heart;    seizure;    hemodialysis;    epilepsia;    morte súbita;    coração;    crises epilépticas;    hemodiálise;   

DOI  :  10.1590/S0004-282X2009000200007

来源: SciELO

【 摘 要 】

Of the many risk factors suggested for sudden unexpected death in epilepsy (SUDEP), higher frequency of seizures is a very consistent issue. Following this reasoning, it has been established that hemodialysis-associated seizure is a complication of dialysis procedure. Based on these facts, this study investigated a possible association between cardiovascular abnormalities and SUDEP among patients with chronic renal insufficiency in regular hemodialysis program. For that, a retrospective medical history of 209 patients was reviewed to investigate the occurrence of convulsive seizures and EKG abnormalities during dialytic program. Three patients presented generalized tonic-clonic seizures, one had partial seizure with secondary generalization, and one presented unclassified seizure. Any EKG abnormalities and SUDEP event were found in all patients evaluated. In conclusion, the present findings demonstrated uncommon the occurrence of seizures and also SUDEP. Probably, the main justification to not allow us to demonstrated a direct relation between SUDEP and cardiovascular diseases in hemodialysis are the reduced number of cases examined.

【 授权许可】

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