Evolution of non-treated restless legs syndrome

Arquivos de Neuro-Psiquiatria

Raimundo Nonato Delgado Rodrigues²  Aída Alexandra Alvim De Abreu E Silva Rodrigues²  Jorge Faber¹  Jeana T. Corso¹  Thaisa F. Peixoto¹ 

[1] ,University of Brasília Hospital Universitário de Brasília Sleep Disorders CenterBrasília DF ,Brazil

关键词: restless legs syndrome;    IRLS;    outcome;    clinical course;    long-term evolution;    treatment;    age;    síndrome das pernas inquietas;    IRLS;    curso clínico;    tratamento;    idade;   

DOI  :  10.1590/S0004-282X2009000100005

来源: SciELO

【 摘 要 】

PURPOSE: The primary concern of this study is to evaluate the clinical course of restless legs syndrome (RLS) in a group of patients who refused treatment. METHOD: This study compares the outcome of a group of RLS patients after one year without any specific treatment. The International Restless Legs Syndrome Scale (IRLS) was applied at baseline (irls_1) and after one year (irls_2). The patients answered a simple questionnaire for the evaluation of possible environmental or life habit changes after one-year evolution. Serum ferritin was determined at baseline. An improvement index (%improvement) was established through the formula: irls_1- irls_2/irls_1 ' 100. Results were compared and a correlation analysis performed. RESULTS: A negative significant correlation was found between the patientsí age and irls_2 (r= -0.9 p=0.0018) and between %improvement and irls_2 (r= -0.88 p=0.0039). A positive and significant correlation was determined between %improvement and age. There was only a marginally significant correlation between serum ferritin and ilrs_2 (r= -0.7 p=0.052). No significant changes were found in the other elements analyzed. CONCLUSION: A favorable outcome was found in this group of RLS patients after one year evolution without treatment. The outcome was positively influenced by the patientsí age.

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