Mesial temporal sclerosis in children

Arquivos de Neuro-Psiquiatria

Eliana Maria Domingues Brandão²  Maria Luiza Giraldes De Manreza¹ 

[1] ,Universidade de São Paulo Faculdade de Medicina Hospital das Clínicas

关键词: temporal lobe epilepsy;    child;    adolescent;    sclerosis;    hippocampus;    epilepsia do lobo temporal;    criança;    adolescente;    esclerose;    hipocampo;   

DOI  :  10.1590/S0004-282X2007000600004

来源: SciELO

【 摘 要 】

Mesial temporal sclerosis is the most frequent cause of drug-resistant temporal lobe epilepsy but has a satisfactory response to surgery, and is considered infrequent in children. OBJECTIVE: To evaluate the clinical, electrographic and radiological spectrum of the disease in children. METHOD: Retrospective study by review of charts of 44 children with a diagnosis of mesial temporal sclerosis on magnetic resonance imaging, attended at the "Hospital das Clínicas" of the University of São Paulo Faculty of Medicine. RESULTS: Febrile seizure was identified in the history of 54% of the patients. Injuries at the left side predominated in patients with schooling difficulties (p=0.049), in those with the first seizures between six months and five years (p=0.021) and in those with complex febrile seizure (p=0.032). Thirteen patients were submitted to surgery and of these, eight remained without seizures. CONCLUSION: Febrile seizure may be related in a more direct way to the presence of left-side mesial temporal sclerosis.

【 授权许可】

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