Syndromes related to sodium and arginine vasopressin alterations in post-operative neurosurgery

Arquivos de Neuro-Psiquiatria

Ana P.d. Cardoso¹  Desanka Dragosavac¹  Sebastião Araújo¹  Antonio L.e. Falcão¹  Renato G.g. Terzi¹  Margaret De Castro²  Fabiana G. Marcondes¹  Taís G. Melo¹  Rosmari A.r.a. Oliveira¹  Eliana A. Cintra¹ 

[1] ,State University of Campinas School of Medical Sciences Department of SurgeryCampinas SP ,Brazil

关键词: cerebral salt wasting syndrome;    syndrome of inappropriate antidiuretic hormone secretion;    diabetes insipidus;    mixed syndrome;    neurosurgery;    síndrome perdedora de sal;    síndrome de secreção inapropriada de hormônio antidiurético;    diabetes insipidus;    síndrome mista;    neurocirurgia;   

DOI  :  10.1590/S0004-282X2007000500003

来源: SciELO

【 摘 要 】

BACKGROUND: Cerebral salt wasting syndrome (CSWS), syndrome of inappropriate antidiuretic hormone secretion (SIADH) and diabetes insipidus (DI) are frequently found in postoperative neurosurgery. PURPOSE: To identify these syndromes following neurosurgery. METHOD: The study included 30 patients who had been submitted to tumor resection and cerebral aneurysm clipping. Sodium levels in serum and urine and urine volume were measured daily up to the 5th day following surgery. Plasma arginine vasopressin (AVP) was measured on the first, third and fifth days post-surgery. RESULTS: CSWS was found in 27/30 patients (90%), in 14 (46.7%) of whom it was associated with a reduction in the levels of plasma AVP (mix syndrome). SIADH was found in 3/30 patients (10%). There was no difference between the two groups of patients. CONCLUSION: CSWS was the most common syndrome found, and in half the cases it was associated with DI. SIADH was the least frequent syndrome found.

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