Validation of the brazilian version of Guy's neurological disability scale

Arquivos de Neuro-Psiquiatria

Carolina R. Araujo¹  Luciano M. Simão¹  Mariana I. Ybarra¹  Natasha V.m.g. Faria¹  Caroline M. Botelho¹  Marcos A. Moreira¹  Antônio L. Teixeira¹  Marco A. Lana-peixoto¹ 

[1] ,Universidade Federal de Minas Gerais Faculdade de Medicina Departamento de OftalmologiaBelo Horizonte MG ,Brasil

关键词: multiple sclerosis;    Guy's neurological disability scale;    expanded disability status scale (EDSS);    disability;    esclerose múltipla;    escala de incapacidade neurológica de Guy;    EDSS;    incapacidade;   

DOI  :  10.1590/S0004-282X2007000400013

来源: SciELO

【 摘 要 】

The Guy's neurological disability scale (GNDS) has recently been introduced as a new measure of disability in multiple sclerosis. It is patient-oriented, multidimensional, and not biased towards any particular disability. The purpose of the present study was to validate the Brazilian version of the GNDS. The adaptation of the scale was based on the translation/back-translation methodology. Sixty-two patients with clinically definite multiple sclerosis (CDMS) according to Poser's criteria were recruited for this study. GNDS was administered individually to each subject. The EDSS and the ambulation index (AI) scores were assigned by a neurologist. The intraclass correlation coefficient and the Cronbach's alpha values of the Brazilian version of GNDS (0.94 and 0.83, respectively) were comparable to the original one (0.98 and 0.79, respectively). Furthermore, the factor analysis of the Brazilian version of GNDS suggested, as the original article, a four-factor solution which accounted for 68.8% of the total variance. The Brazilian version of GNDS was found to be clinically relevant as it correlated significantly with the EDSS and AI. In conclusion, the Brazilian version of GNDS can be considered an important tool to evaluate the disability in MS patients, with clinical usefulness and psychometrics soundness.

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