Kleine-Levin syndrome: interface between neurology and psychiatry

Arquivos de Neuro-Psiquiatria

Luís Pereira Justo¹  Helena Maria Calil¹  Sílvia A. Prado-bolognani¹  Mauro Muszkat¹ 

[1] ,Federal University of São Paulo Department of Pychobilogy São Paulo SP ,Brazil

关键词: Kleine-Levin;    neuropsychology;    polysomnography;    risperidone;    sleep disorders;    Kleine-Levin;    neuropsicologia;    polissonografia;    risperidona;    transtorno de sono;   

DOI  :  10.1590/S0004-282X2007000100030

来源: SciELO

【 摘 要 】

We report the first episode of Kleine-Levin (KLS) syndrome in a 17-year-old male. The illness onset, clinical features, neuropsychological evaluation and polysomnographic recording are described. Typical symptoms hypersomnia, hyperphagia and sexual disinhibition were observed besides behavioral disturbances, polysonographic and neuropsychological alterations. Behavioral disturbances similar to a manic episode including psychotic symptoms were relevant. The pharmacologic treatment included lithium, methylphenidate and risperidone. The introduction of risperidone aimed the control of psychotic symptoms and the persistent manifestations of hypersexuality after sleepness control and to the best of our knowledge there are no other report regarding risperidone use for KLS in the literature.

【 授权许可】

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