Outcome of sleepiness and fatigue scores in obstructive sleep apnea syndrome patients with and without restless legs syndrome after nasal CPAP

Arquivos de Neuro-Psiquiatria

Raimundo Nonato Delgado Rodrigues²  Aída Alexandra Alvim De Abreu E Silva Rodrigues²  Riccardo Pratesi¹  Marília Miranda Fortes Gomes¹  Ana Maria Nogales Vasconcelos¹  Christine Erhardt¹  Jean Krieger¹ 

[1] ,Hospital Universitário de BrasíliaBrasília DF ,Brazil

关键词: OSAS;    RLS;    fatigue;    sleepiness;    ESS;    Pichot;    SAOS;    síndrome das pernas inquietas;    fadiga;    sonolência;    escala de sonolência de Epworth;    Pichot;   

DOI  :  10.1590/S0004-282X2007000100012

来源: SciELO

【 摘 要 】

BACKGROUND & PURPOSE: The association of obstructive sleep apnea syndrome (OSAS) and restless legs syndrome (RLS) has been reported in the literature for many years. Both conditions may be responsible for fatigue and somnolence complaints secondary to nocturnal sleep disruption. The primary concern of this study is to evaluate the outcome of fatigue and daytime sleepiness symptoms at baseline and after continuous positive air pressure (CPAP) treatment in OSAS patients with and without RLS. METHOD: A prospective and comparative study between a group of 13 patients with OSAS and a group of 17 patients with OSAS+RLS. Laboratory blood tests and polysomnography were performed at baseline. The Epworth Sleepiness Scale (ESS) and the Pichot’s questionnaire of fatigue/depression (PIC) were applied before and after 3 months of CPAP treatment. Results were compared. RESULTS: No significant differences were found on PSG and laboratory results at baseline. Both groups had similar ESS and PIC scores at baseline (p=0.73 and 0.08, respectively). After n-CPAP, OSAS+RLS patients showed higher ESS and PIC scores (p=0.017 and 0.03, respectively). CONCLUSIONS: Despite a favorable general response, n-CPAP seemed less effective in treating fatigue and sleepiness in the OSAS+RLS group.

【 授权许可】

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