Intrasellar pressure and tumor volume in pituitary tumor: relation study

Arquivos de Neuro-Psiquiatria

Jackson A. Gondim²  Osvaldo I. Tella Jr.¹  Michele Schops¹ 

[1] ,Hospital of Fortaleza Neurosurgery Department General Fortaleza CE ,Brazil

关键词: pituitary adenoma;    intrasellar pressure;    endonasal approach;    adenoma hipofisário;    pressão intra-selar;    via transesfenoidal;   

DOI  :  10.1590/S0004-282X2006000600016

来源: SciELO

【 摘 要 】

OBJECTIVE: To determine if there was a relationship between intrassellar pressure (ISP) and pituitary tumor volume. METHOD: Between August 2002 and May 2004, 60 patients aged between 13 and 75 years old (39 males), having a pituitary adenoma were submitted to an endoscope transseptal approach. During the surgery and before tumor resection, 2 mm of the sella’s floor were removed and a 1.5 mm dural opening made to place a transducer into the pituitary adenoma. The transducer was connected to a pressure monitor. RESULTS: The intrasellar pressure, ranged from 2-51 mmHg and was measured based on the classification of Hardy-Vezina. The most elevated was in the type II macro adenomas with 32.6 mmHg, sharply superior to the value of a normal intracranial pressure. CONCLUSION: These values showed that the macroadenomas confined to the sella, without destruction of the floor and integrity of the diaphragm, type II of Hardy-Vezina, presented a value of ISP much higher than intra-extrasellar macroadenoma’s.

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