Quantitative aspects of brain perfusion dynamic induced by BOLD fMRI

Arquivos de Neuro-Psiquiatria

Katia C. Andrade²  Octavio M. Pontes-neto¹  Joao P. Leite¹  Antonio Carlos Santos¹  Oswaldo Baffa²  Draulio B. De Araujo² 

[1] ,USP FFCLRP Dept. of Physics and MathRibeirão Preto SP ,Brazil

关键词: functional MRI;    fMRI;    BOLD;    perfusion;    ressonância magnética funcional;    fMRI;    BOLD;    perfusão;   

DOI  :  10.1590/S0004-282X2006000600001

来源: SciELO

【 摘 要 】

The increase of relative cerebral blood flow (rCBF) may contribute for a change in blood oxygenation level dependent signal (BOLD). The main purpose of this study is to investigate some aspects of perfusional alterations in the human brain in response to a uniform stimulation: hypercapnia induced by breath holding. It was observed that the BOLD signal increased globally during hypercapnia and that it is correlated with the time of breath holding. This signal increase shows a clear distinction between gray and white matter, being greater in the grey matter.

【 授权许可】

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