CSF markers for diagnosis of bacterial meningitis in neurosurgical postoperative patients

Arquivos de Neuro-Psiquiatria

Wagner Malagó Tavares¹  Andre Guelman Machado¹  Hamilton Matushita¹  Jose Pindaro P. Plese¹ 

[1] ,University of São Paulo Medical School Division of NeurosurgerySão Paulo SP ,Brazil

关键词: CSF;    bacterial meningitis;    neurosurgery;    ROC analysis;    postoperative infection;    meningite bacteriana;    LCR;    neurocirurgia;    curva ROC;    infecção pós-operatória;   

DOI  :  10.1590/S0004-282X2006000400012

来源: SciELO

【 摘 要 】

OBJECTIVE: To evaluate the diagnostic usefulness of cerebral spinal fluid (CSF) cellularity, protein, neutrophils, glucose and lactate for detection of postoperative bacterial meningitis. METHOD: This prospective study was conducted in 28 postoperative neurosurgical patients from 2002 to 2005 at University of São Paulo. The CSF markers were plotted in a receiver operating characteristic (ROC) curve to evaluate their accuracy. RESULTS: Based on the area under ROC curve CSF glucose, cellularity, and lactate were considered good tests. Polymorphonuclear and protein did not achieve enough accuracy to be used clinically. CONCLUSION: The CSF glucose, lactate, and cellularity can be used for the diagnosis of bacterial meningitis. Moreover, it can be helpful to differentiate bacterial from aseptic meningitis.

【 授权许可】

CC BY   
 All the contents of this journal, except where otherwise noted, is licensed under a Creative Commons Attribution License