Comparative clinical study of preterm and full-term newborn neonatal seizures

Arquivos de Neuro-Psiquiatria

Manoel R.r. Holanda²  Áurea N. De Melo¹ 

[1] ,Universidade Federal do Rio Grande do NorteNatal RN ,Brazil

关键词: neonatal seizures;    gestational age;    comparative study;    neonate;    preterm infant;    full-term infant;    convulsões neonatais;    idade gestacional;    estudo comparativo;    neonatos pretermo;    neonatos de termo;   

DOI  :  10.1590/S0004-282X2006000100010

来源: SciELO

【 摘 要 】

OBJECTIVE: To compare the characteristics of neonatal seizures between preterm and full-term infants in intensive care unit. METHOD: A prospective study was developed with 104 high-risk newborn, 30 preterm and 74 full-term infants, with clinical seizures. The dependent variable was gestational age. Statistical analyses: Fisher's exact test, odds-ratio and Mann Witney U test. RESULTS: There were significant differences (p<0.05): i) premature neonates develop neonatal seizures later, probably related to the etiologies of the seizures; ii) etiologically, there is a predominance of peri-intraventricular hemorrhage in preterm and of asphyxia in full term neonates; iii) clonic seizures are most frequent in preterm and subtle seizures in full term neonates. CONCLUSION: Although the study had a clinical basis, it was possible to identify differences when the dependent variable was gestational age.

【 授权许可】

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