Thrombolytic therapy for acute extra-cranial artery dissection: report of two cases

Arquivos de Neuro-Psiquiatria

Osama O. Zaidat¹  Jose Americo M. Fernandes Filho¹  Gurwant Singh¹  Jose I. Suarez¹ 

[1] ,Case Western Reserve University University Hospitals of Cleveland Departament of Neurology

关键词: thrombolysis;    stroke;    dissection;    internal carotid artery;    trombólise;    acidente vascular cerebral;    dissecção;    artéria carótida interna;   

DOI  :  10.1590/S0004-282X2001000600018

来源: SciELO

【 摘 要 】

Extra-cranial arterial dissection accounts for 10% of strokes in young people. Information on safety of thrombolytic administration in this group is limited. The literature, however, does not favor use of thrombolytics for myocardial ischemia when peripheral arterial dissection coexists. Based on the clinical and radiological features, two patients who presented with acute stroke secondary to arterial dissection were considered for thrombolysis. One of them received intra-venous recombinant tissue plasminogen activator (rtPA), and the other patient received intra-arterial rtPA. There were no post thrombolysis complications. This report supports feasibility of administering thrombolytics in acute ischemic strokes resulting from extra-cranial arterial dissection. Future larger studies are necessary to determine the efficacy, safety and long-term outcome in this patient population.

【 授权许可】

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