Epileptic manifestations induced by midazolam in the neonatal period

Arquivos de Neuro-Psiquiatria

Maria Augusta Montenegro¹  Marilisa M. Guerreiro¹  Jamil Pedro Siqueira Caldas¹  Maria Valeriana L. Moura-ribeiro¹  Carlos Alberto M. Guerreiro¹ 

[1] ,University of Campinas Faculty of Medical Sciences Department of NeurologyCampinas SP ,Brazil

关键词: midazolam;    seizures;    neonatal period;    midazolam;    crise epiléptica;    período neonatal;   

DOI  :  10.1590/S0004-282X2001000200018

来源: SciELO

【 摘 要 】

Antiepileptic drugs may cause worsening of epilepsy by aggravating pre-existing seizures or by triggering new seizure types. There are several reports of adverse effects related to midazolam, but only a few authors reported epileptic manifestations. We report four newborns seen at the Neonatal Intensive Care Unit of our University Hospital, who developed seizures a few seconds after the administration of midazolam. It is difficult to identify the patients at risk, but it is important to be aware and recognize this situation.

【 授权许可】

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