Pilocytic astrocytoma following radiotherapy for craniopharyngioma: case report

Arquivos de Neuro-Psiquiatria

Leonardo Bonilha¹  Guilherme Borges²  Yvens B. Fernandes²  Ricardo Ramina²  Edmur F Carelli²  Marcelo Alvarenga¹ 

[1],Universidade Estadual de Campinas Faculdade de Ciências Médicas

关键词: pilocytic astrocytoma;    radiotherapy adverse-effects;    oncogenesis;    astrocitoma pilocítico;    efeitos adversos de radioterapia;    oncogênese;   

DOI  :  10.1590/S0004-282X2000000400022

来源: SciELO

【 摘 要 】

Administration of fractionated doses of irradiation is part of the adjutant therapy for CNS tumours such as craniopharyngiomas and pituitary adenomas. It can maximise cure rates or expand symptom-free period. Among the adverse effects of radiotherapy, the induction of a new tumour within the irradiated field has been frequently described. The precise clinical features that correlate irradiation and oncogenesis are not completely defined, but some authors have suggested that tumors are radiation induced when they are histologically different from the treated ones, arise in greater frequency in irradiated patients than among normal population and tend to occur in younger people with an unusual aggressiveness. In this article, we report a case of a papillary astrocytoma arising in a rather unusual latency period following radiotherapy for craniopharyngioma.

【 授权许可】

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