Brain SPECT imaging in Huntington's disease before and after therapy with olanzapine: case report

Arquivos de Neuro-Psiquiatria

Elba C. S. C. Etchebehere²  Mariana C. L. Lima²  Walmir Passos¹  Jaime A. Maciel Jr¹  Allan O. Santos²  Celso DarÍo Ramos²  Edwaldo E. Camargo² 

[1] ,Universidade Estadual de Campinas (UNICAMP) Faculdade de Ciências Médicas (FCM) Department of Radiology

关键词: Huntington's disease;    brain SPECT;    olanzapine;    basal ganglia;    99mTc-HMPAO;    doença de Huntington;    SPECT cerebral;    olanzapina;    núcleos da base;    HMPAO-99mTc;   

DOI  :  10.1590/S0004-282X1999000500021

来源: SciELO

【 摘 要 】

Olanzapine, an atypical antipsychotic drug, was administered to a patient with Huntington's disease (HD) with marked choreiform movements. Brain SPECT with 99mTc-HMPAO was performed before and after treatment. Brain SPECT imaging has been performed in patients with HD in order to determine the status of basal ganglia perfusion. The use of brain SPECT with 99mTc-HMPAO before and after treatment in patients with HD has not been yet reported. The marked hypoperfusion of the basal ganglia on brain SPECT performed before therapy with olanzapine improved significantly after treatment.

【 授权许可】

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