Pseudocystic form of neurocryptococcosis in pregnancy: case report

Arquivos de Neuro-Psiquiatria

Anamarli Nucci²  Jayme Antunes Maciel Jr²  Luciano De Souza Queiroz¹  Maria Augusta Montenegro²  Rita Barbosa De Carvalho¹ 

[1] ,State University of Campinas, Medical School Departments of Neurology

关键词: neurocryptococcosis;    neurocysticercosis;    pregnancy;    pseudocysts;    neurocriptococose;    neurocisticercose;    gravidez;    pseudocistos;   

DOI  :  10.1590/S0004-282X1999000400023

来源: SciELO

【 摘 要 】

We report a case of neurocryptococcosis which is unique in the literature because the patient had a pseudocystic form of the disease during pregnancy and without any evidence of AIDS. The clinical picture was that of intracranial hypertension and the epidemiological background was highly suggestive of cysticercosis. CT showed multiple round hypodense lesions in the basal ganglia and cerebellum, without contrast enhancement. Since a scolex was not visible, the diagnosis of neurocysticercosis was considered probable. CSF examination was not performed in view of its high risk. The patient had progressive downhill course. Autopsy disclosed multiple gelatinous pseudocysts in the cerebral and cerebellar gray matter, containing abundant Cryptococcus neoformans. Meningeal involvement was minimal. The child was delivered by caesarean section and was free of infection, but died later of hyaline membrane disease. The neuroimaging appearances of this rare instance of the pseudocystic form of neurocryptococcosis mimicked closely neurocysticercosis and only postmortem examination allowed correct diagnosis. The pseudocystic form has so far only been reported in AIDS.

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